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Predictive
Genomic Profiles
by Genovation
Patient's
Guide to Genomics
CardioGenomicSM
Profile
Identifies genetic single nucleotide polymorphisms associated with
increased risk of developing atherosclerosis, hypertension, and
coronary artery disease. Risk factors include methylation defects,
iron overload, hyper-coagulation syndromes, cholesterol regulation
defects, inflammation, general risk markers and cardio-protective
markers.
OsteoGenomicSM
Profile
Identifies genetic single nucleotide polymorphisms associated with
increased risk of developing osteopenia and osteoporosis. Risk factors
include collagen synthesis, calcium metabolism, vitamin D3 activity,
parathyroid hormone action, osteoclastic activity, and chronic inflammation.
DetoxiGenomicSM
Profile
Identifies genetic single nucleotide polymorphisms associated with
increased risk of developing detoxification defects especially with
increased exposure to xenobiotics and other toxins. Risk factors
include altered cytochrome P-450 activity in phase 1 detoxification,
impaired glutathione conjugation and acetylation in phase 2 reactions,
altered catecholamine methylation and increased oxidative stress.
Detoxification defects have been associated with increased risk
for certain cancers, chronic fatigue, multiple chemical sensitivity,
and alcoholism.
ImmunoGenomicSM
Profile
Identifies genetic single nucleotide polymorphisms associated with
increased risk of developing defects in immune competence and surveillance.
Risk factors include altered interleukin production and activity
within the body and increased production of other cytokines like
tissue necrosis factor alpha that may lead to conditions characterized
by chronically up-regulated inflammatory response. Immunologic polymorphisms
have been associated with increased risk of asthma, atopy, osteopenia,
heart disease, and infectious diseases.
Patient's
Guide to Genomics
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